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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTK6 All Species: 14.35
Human Site: T445 Identified Species: 35.08
UniProt: Q13882 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13882 NP_005966.1 451 51834 T445 R E R L S S F T S Y E N P T _
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001114081 399 45435
Dog Lupus familis XP_865870 536 59880 T526 L E D Y F T S T E P Q Y Q P G
Cat Felis silvestris
Mouse Mus musculus Q64434 451 51954 T445 C E K L T G I T R Y E N L V _
Rat Rattus norvegicus Q9WUD9 536 60060 T526 L E D Y F T S T E R Q Y Q P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506767 453 52558 T447 K E K L F C F T N Y E N P G _
Chicken Gallus gallus P09324 541 60774 T531 L E D Y F T A T E P Q Y Q P G
Frog Xenopus laevis P13116 532 59718 T522 L E D Y F T A T E P Q Y Q P G
Zebra Danio Brachydanio rerio NP_001070140 511 58156 Q503 K D E L D N Y Q G Q Y S S V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9J3 517 59051 Y504 Q W K L E D F Y T S D Q S D Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 78.7 39.7 N.A. 80 39.1 N.A. 67.9 37.8 38.7 42.4 N.A. 40.8 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 80.9 52.9 N.A. 89.8 52.7 N.A. 80.5 53.9 53.7 60.4 N.A. 55.9 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 0 13.3 N.A. 42.8 13.3 N.A. 57.1 13.3 13.3 6.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 0 33.3 N.A. 57.1 33.3 N.A. 78.5 33.3 33.3 46.6 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % A
% Cys: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 40 0 10 10 0 0 0 0 10 0 0 10 0 % D
% Glu: 0 70 10 0 10 0 0 0 40 0 30 0 0 0 0 % E
% Phe: 0 0 0 0 50 0 30 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 10 0 0 0 0 10 50 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 20 0 30 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 40 0 0 50 0 0 0 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 10 0 0 30 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 30 0 0 20 40 0 % P
% Gln: 10 0 0 0 0 0 0 10 0 10 40 10 40 0 0 % Q
% Arg: 10 0 10 0 0 0 0 0 10 10 0 0 0 0 0 % R
% Ser: 0 0 0 0 10 10 20 0 10 10 0 10 20 0 0 % S
% Thr: 0 0 0 0 10 40 0 70 10 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 40 0 0 10 10 0 30 10 40 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30 % _